Research Topic
Some chaperone-mediated events in stressed and non-stressed cells
Our group is interested in the proteins of the molecular stress response, the molecular chaperones. These proteins are characterised by their stress-protective function. They also have functions under normal growth conditions. Using the model organism Caenorhabditis elegans we investigate the participation of Hsp90 and its cofactors during development and attempt to uncover the biochemical mechanisms.
Research projects
Mechanism of the Hsp90 system in Caenorhabditis elegans
Mechanism of the C. elegans Hsc70 Systems
Heat shock response and protein aggregation
Chemical modulation of the chaperone system
Analytical ultracentrifugation